STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1640Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 74.78; identified by sequence similarity; putative. (468 aa)    
Predicted Functional Partners:
TM_1639
Electron transfer protein, putative; Similar to GB:L77117 PID:1592091 percent identity: 57.64; identified by sequence similarity; putative; Belongs to the PyrK family.
 0.999
glnA
Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under [...]
  
 
 0.996
gltB
Glutamate synthase, alpha subunit; Similar to GB:AE000782 percent identity: 81.16; identified by sequence similarity; putative; Belongs to the glutamate synthase family.
 
 0.994
gdhA
Glutamate dehydrogenase; Similar to PID:1743418 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.994
carB
Carbamoyl-phosphate synthase, large subunit; Similar to GB:AE000782 percent identity: 78.50; identified by sequence similarity; putative.
  
 
 0.992
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
 
 
 0.991
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.991
carA
Carbamoyl-phosphate synthetase, small subunit; Similar to GB:AE000657 percent identity: 75.35; identified by sequence similarity; putative; Belongs to the CarA family.
    
 0.991
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.991
aspC
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 66.22; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.991
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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