STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1640Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 74.78; identified by sequence similarity; putative. (468 aa)    
Predicted Functional Partners:
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
 
 0.999
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
 
 0.999
TM_1639
Electron transfer protein, putative; Similar to GB:L77117 PID:1592091 percent identity: 57.64; identified by sequence similarity; putative; Belongs to the PyrK family.
 
 0.999
TM_0228
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 72.27; identified by sequence similarity; putative.
 
 0.995
gltB
Glutamate synthase, alpha subunit; Similar to GB:AE000782 percent identity: 81.16; identified by sequence similarity; putative; Belongs to the glutamate synthase family.
 
 0.994
glnA
Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. Under [...]
  
 
 0.980
TM_0394
Conserved hypothetical protein; Similar to GB:L77117 PID:1591993 percent identity: 74.00; identified by sequence similarity; putative.
  
 0.968
TM_0398
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 77.22; identified by sequence similarity; putative.
  
 0.968
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
 0.964
gdhA
Glutamate dehydrogenase; Similar to PID:1743418 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.961
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.