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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1654Sensor histidine kinase HpkA; Similar to PID:1575578 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative. (412 aa)    
Predicted Functional Partners:
TM_1655
Response regulator DrrA; Similar to PID:1575577 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative.
 0.998
cheR
Chemotactic methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
   
 0.932
TM_0399
Response regulator; Similar to SP:Q44006 percent identity: 65.92; identified by sequence similarity; putative.
 0.930
TM_0468
Response regulator; Similar to PID:1575577 GB:AE000512 percent identity: 69.17; identified by sequence similarity; putative.
 0.920
TM_1259
Phosphate regulon transcriptional regulatory protein PhoB; Similar to GB:M31793 SP:P45606 PID:152773 percent identity: 63.64; identified by sequence similarity; putative.
 0.901
TM_1360
Response regulator; Similar to GB:L09228 SP:P35163 PID:410141 GB:AL009126 percent identity: 65.79; identified by sequence similarity; putative.
 
 0.890
TM_0126
Response regulator; Similar to GB:M16775 SP:P13792 GB:X67676 PID:143328 PID:143330 percent identity: 60.09; identified by sequence similarity; putative.
 0.870
TM_1652
Hypothetical protein; Identified by sequence similarity; putative.
  
    0.831
TM_1653
Pyrimidine-nucleoside phosphorylase; Similar to SP:P77836 PID:1620901 PID:1638805 percent identity: 74.48; identified by sequence similarity; putative.
  
  
 0.830
TM_1651
Translation elongation factor G; Similar to GB:AE000657 percent identity: 66.37; identified by sequence similarity; putative; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
       0.822
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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