STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1660Conserved hypothetical protein; Similar to PID:1772609 GB:AE000512 percent identity: 99.68; identified by sequence similarity; putative. (323 aa)    
Predicted Functional Partners:
TM_1659
Hypothetical protein; Identified by sequence similarity; putative.
       0.827
surE
Stationary phase survival protein; Nucleotidase that preferentially dephosphorylates 5'-GMP and 5'-AMP.
  
  
 0.772
def
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
       0.763
TM_1665
Hypothetical protein; Identified by sequence similarity; putative.
  
  
 0.763
ecfA1
ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex.
  
    0.757
TM_1664
Conserved hypothetical protein; Similar to PID:1499712 GB:L77117 PID:1499712 percent identity: 66.33; identified by sequence similarity; putative.
       0.752
TM_1666
Succinyl-diaminopimelate desuccinylase, putative; Similar to GB:AE000782 percent identity: 71.21; identified by sequence similarity; putative.
       0.752
TM_0409
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 58.61; identified by sequence similarity; putative.
  
     0.751
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
       0.638
TM_1686
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 58.90; identified by sequence similarity; putative.
  
 
 0.594
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.