STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_1664Conserved hypothetical protein; Similar to PID:1499712 GB:L77117 PID:1499712 percent identity: 66.33; identified by sequence similarity; putative. (210 aa)    
Predicted Functional Partners:
ecfA1
ABC transporter, ATP-binding protein; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (Probable). Expression of the complex plus RibU in E.coli allows riboflavin uptake; uptake does not occur in the absence of RibU or the EcfA1A2T complex.
  
    0.840
def
Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
       0.813
surE
Stationary phase survival protein; Nucleotidase that preferentially dephosphorylates 5'-GMP and 5'-AMP.
       0.813
TM_1665
Hypothetical protein; Identified by sequence similarity; putative.
       0.813
TM_1666
Succinyl-diaminopimelate desuccinylase, putative; Similar to GB:AE000782 percent identity: 71.21; identified by sequence similarity; putative.
       0.813
TM_1659
Hypothetical protein; Identified by sequence similarity; putative.
       0.752
TM_1660
Conserved hypothetical protein; Similar to PID:1772609 GB:AE000512 percent identity: 99.68; identified by sequence similarity; putative.
       0.752
obg
Conserved hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
   
    0.615
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.566
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.559
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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