Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TM_1692Aminotransferase, class V; Similar to SP:P12623 PID:142037 percent identity: 62.03; identified by sequence similarity; putative. (384 aa)    
Predicted Functional Partners:
iscU
Nitrogen fixation protein NifU-related protein; A scaffold on which IscS assembles Fe-S clusters. Subsequently gives the nascent cluster to other proteins. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (By similarity). Belongs to the NifU family.
 
 0.999
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.997
TM_0978
Conserved hypothetical protein; Similar to GB:L77117 SP:Q58397 PID:1591652 percent identity: 56.94; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
   
 0.863
TM_0983
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 66.23; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
   
 0.862
TM_1693
1-acyl-sn-glycerol-3-phosphate acetyltransferase, putative; Similar to GB:L32861 PID:520780 GB:AE000783 percent identity: 57.75; identified by sequence similarity; putative; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
       0.813
TM_0567
Conserved hypothetical protein; Similar to PID:633731 percent identity: 58.96; identified by sequence similarity; putative.
  
 
 0.792
TM_1527
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 54.92; identified by sequence similarity; putative.
  
 
 0.792
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.769
acpP-2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 
 0.769
TM_1687
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
  0.769
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.