STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1697Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 64.88; identified by sequence similarity; putative. (391 aa)    
Predicted Functional Partners:
TM_1698
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 53.25; identified by sequence similarity; putative.
       0.827
TM_1696
Type IV prepilin peptidase; Similar to GB:AE000657 percent identity: 61.90; identified by sequence similarity; putative.
  
    0.814
TM_1695
Conserved hypothetical protein; Similar to GB:AE000666 percent identity: 53.37; identified by sequence similarity; putative.
       0.810
TM_1699
Conserved hypothetical protein; Similar to PID:558266 percent identity: 62.23; identified by sequence similarity; putative.
       0.773
TM_1693
1-acyl-sn-glycerol-3-phosphate acetyltransferase, putative; Similar to GB:L32861 PID:520780 GB:AE000783 percent identity: 57.75; identified by sequence similarity; putative; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
       0.566
TM_1692
Aminotransferase, class V; Similar to SP:P12623 PID:142037 percent identity: 62.03; identified by sequence similarity; putative.
       0.547
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.546
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
    0.491
TM_1686
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 58.90; identified by sequence similarity; putative.
       0.482
TM_1691
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 53.26; identified by sequence similarity; putative.
       0.477
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.