Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TM_1698Aspartate aminotransferase; Similar to PID:1255699 percent identity: 53.25; identified by sequence similarity; putative. (397 aa)    
Predicted Functional Partners:
TM_1217
Glutamate synthase, beta subunit; Similar to PID:2244618 percent identity: 58.52; identified by sequence similarity; putative.
  
 
 0.973
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. It is stereospecific for L(+)-lactate.
  
 0.969
TM_0155
Chorismate mutase/prephenate dehydratase; Similar to GB:AE000782 percent identity: 80.45; identified by sequence similarity; putative.
  
 
 0.968
gdhA
Glutamate dehydrogenase; Similar to PID:1743418 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.966
aspC
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 66.22; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.963
TM_0547
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 67.00; identified by sequence similarity; putative.
  
 0.962
argG
Argininosuccinate synthase; Similar to SP:P16460 PID:192065 PID:192066 PID:309111 PID:553871 percent identity: 76.79; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.962
TM_0344
Prephenate dehydrogenase; Similar to PID:1653053 percent identity: 49.42; identified by sequence similarity; putative.
  
 
 0.960
hisC
Histidinol-phosphate aminotransferase; Similar to GB:AE000657 percent identity: 59.04; identified by sequence similarity; putative; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.960
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 0.959
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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