STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1704Hypothetical protein; Identified by sequence similarity; putative. (581 aa)    
Predicted Functional Partners:
lysS
lysyl-tRNA synthetase; Similar to PID:567884 SP:Q53638 percent identity: 72.67; identified by sequence similarity; putative; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.831
TM_1735
Conserved hypothetical protein; Similar to PID:1001350 PID:1001356 percent identity: 50.28; identified by sequence similarity; putative.
 
  
 0.808
greA
Transcription elongation factor, greA/greB family; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
    0.807
nrdR
Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.803
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation. Belongs to the WhiA family.
       0.803
TM_1709
Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
       0.803
TM_1703
Conserved hypothetical protein; Similar to SP:P54496 PID:1303866 GB:AL009126 percent identity: 56.61; identified by sequence similarity; putative.
     
 0.788
TM_0181
Hypothetical protein; Identified by sequence similarity; putative.
 
    0.778
TM_0806
Hypothetical protein; Identified by sequence similarity; putative.
  
     0.773
TM_1178
Acetyltransferase-related protein; Similar to GB:AE000657 percent identity: 50.40; identified by sequence similarity; putative.
  
     0.771
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.