Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TM_1753Excinuclease ABC, subunit B-related protein; Similar to GB:AE000657 percent identity: 77.48; identified by sequence similarity; putative. (99 aa)    
Predicted Functional Partners:
uvrA
Excinuclease ABC, subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.985
uvrC
Excinuclease ABC, subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 0.981
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.571
TM_1757
Hypothetical protein; Identified by sequence similarity; putative.
       0.568
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
     
 0.548
buk1
Butyrate kinase, putative; Similar to GB:L04468 SP:Q05619 PID:144893 percent identity: 64.59; identified by sequence similarity; putative; Belongs to the acetokinase family.
       0.544
TM_1755
Phosphate butyryltransferase; Similar to GB:L14744 PID:457633 percent identity: 63.01; identified by sequence similarity; putative.
       0.544
buk2
Branched-chain-fatty-acid kinase, putative; Similar to SP:P54532 PID:1303940 GB:AL009126 percent identity: 73.60; identified by sequence similarity; putative; Belongs to the acetokinase family.
       0.544
TM_1758
2-oxoisovalerate oxidoreductase, gamma subunit, putative; Similar to GB:AE000666 percent identity: 61.67; identified by sequence similarity; putative.
       0.544
TM_1759
2-oxoisovalerate oxidoreductase, beta subunit, putative; Similar to GB:AE000666 percent identity: 68.12; identified by sequence similarity; putative.
       0.544
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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