Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TM_1755Phosphate butyryltransferase; Similar to GB:L14744 PID:457633 percent identity: 63.01; identified by sequence similarity; putative. (364 aa)    
Predicted Functional Partners:
buk1
Butyrate kinase, putative; Similar to GB:L04468 SP:Q05619 PID:144893 percent identity: 64.59; identified by sequence similarity; putative; Belongs to the acetokinase family.
 
 0.999
buk2
Branched-chain-fatty-acid kinase, putative; Similar to SP:P54532 PID:1303940 GB:AL009126 percent identity: 73.60; identified by sequence similarity; putative; Belongs to the acetokinase family.
 
 0.997
TM_1164
2-oxoacid ferredoxin oxidoreductase, alpha subunit; Similar to GB:AE000666 percent identity: 68.99; identified by sequence similarity; putative.
    
 0.972
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Phosphorylates propionate (54%) in addition to acetate (100%). Uses GTP (100%), ITP (163%), UTP (56%), and CTP (21%) as phosphoryl donors in addition to ATP (100%).
 
 0.912
TM_1759
2-oxoisovalerate oxidoreductase, beta subunit, putative; Similar to GB:AE000666 percent identity: 68.12; identified by sequence similarity; putative.
    
 0.861
TM_1758
2-oxoisovalerate oxidoreductase, gamma subunit, putative; Similar to GB:AE000666 percent identity: 61.67; identified by sequence similarity; putative.
    
 0.810
TM_1757
Hypothetical protein; Identified by sequence similarity; putative.
       0.787
TM_1425
Fe-hydrogenase, subunit beta; Similar to GP:2865516 percent identity: 100.00; identified by sequence similarity; putative.
  
 
 0.754
pgk/tpi
Phosphoglycerate kinase/triose-phosphate isomerase; Similar to PIR:S54289 percent identity: 99.69; identified by sequence similarity; putative; In the N-terminal section; belongs to the phosphoglycerate kinase family.
  
  
 0.605
TM_0010
NADP-reducing hydrogenase, subunit C; Similar to GB:U07229 PID:466365 percent identity: 78.67; identified by sequence similarity; putative.
  
 
 0.574
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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