Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
TM_1757Hypothetical protein; Identified by sequence similarity; putative. (218 aa)    
Predicted Functional Partners:
TM_1759
2-oxoisovalerate oxidoreductase, beta subunit, putative; Similar to GB:AE000666 percent identity: 68.12; identified by sequence similarity; putative.
 
    0.946
TM_1758
2-oxoisovalerate oxidoreductase, gamma subunit, putative; Similar to GB:AE000666 percent identity: 61.67; identified by sequence similarity; putative.
 
     0.945
buk1
Butyrate kinase, putative; Similar to GB:L04468 SP:Q05619 PID:144893 percent identity: 64.59; identified by sequence similarity; putative; Belongs to the acetokinase family.
       0.815
buk2
Branched-chain-fatty-acid kinase, putative; Similar to SP:P54532 PID:1303940 GB:AL009126 percent identity: 73.60; identified by sequence similarity; putative; Belongs to the acetokinase family.
       0.815
TM_1755
Phosphate butyryltransferase; Similar to GB:L14744 PID:457633 percent identity: 63.01; identified by sequence similarity; putative.
       0.787
TM_0406
Keto/oxoacid ferredoxin oxidoreductase, gamma subunit, putative; Similar to GB:L77117 PID:1591240 percent identity: 59.77; identified by sequence similarity; putative.
 
     0.661
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.616
TM_1753
Excinuclease ABC, subunit B-related protein; Similar to GB:AE000657 percent identity: 77.48; identified by sequence similarity; putative.
       0.568
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
     
 0.550
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
   
 
 0.541
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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