Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TM_1776Ferric uptake regulation protein; Similar to GB:L11361 PID:349012 percent identity: 56.52; identified by sequence similarity; putative; Belongs to the Fur family. (152 aa)    
Predicted Functional Partners:
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
 
    0.798
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
  
    0.779
TM_0807
Alkyl hydroperoxide reductase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.580
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.558
TM_1435
Conserved hypothetical protein; Similar to GB:Pyro_h percent identity: 62.39; identified by sequence similarity; putative.
  
    0.529
TM_1779
Hypothetical protein; Identified by sequence similarity; putative.
       0.522
coaD
Lipopolysaccharide core biosynthesis protein KdtB; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
     0.474
TM_0124
Zinc ABC transporter, ATP-binding protein; Part of an ATP-driven transport system TM_0123/TM_0124/TM_0125 for a metal. Probably responsible for energy coupling to the transport system.
  
  
 0.431
argG
Argininosuccinate synthase; Similar to SP:P16460 PID:192065 PID:192066 PID:309111 PID:553871 percent identity: 76.79; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.429
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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