STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argGArgininosuccinate synthase; Similar to SP:P16460 PID:192065 PID:192066 PID:309111 PID:553871 percent identity: 76.79; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa)    
Predicted Functional Partners:
argF
Ornithine carbamoyltransferase, anabolic; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.999
carB
Carbamoyl-phosphate synthase, large subunit; Similar to GB:AE000782 percent identity: 78.50; identified by sequence similarity; putative.
 
 
 0.996
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.993
aspC
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 66.22; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
  
 0.993
TM_1698
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 53.25; identified by sequence similarity; putative.
  
 0.993
pyrBI
Aspartate carbamoyltransferase, catalytic and regulatory chains; Similar to PID:1772605 GB:AE000512 percent identity: 100.00; identified by sequence similarity; putative; In the N-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.991
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
  
  
 0.974
carA
Carbamoyl-phosphate synthetase, small subunit; Similar to GB:AE000657 percent identity: 75.35; identified by sequence similarity; putative; Belongs to the CarA family.
  
 
 0.971
TM_0547
Aspartokinase II; Similar to PID:928811 SP:P53553 percent identity: 67.00; identified by sequence similarity; putative.
  
 
 0.969
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.966
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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