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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggConserved hypothetical protein; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity); Belongs to the type-2 OGG1 family. (207 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.810
TM_1822
ftsH protease activity modulator HflK; HflC and HflK could encode or regulate a protease.
       0.792
TM_1823
ftsH protease activity modulator HflC; HflC and HflK could regulate a protease.
       0.792
TM_1704
Hypothetical protein; Identified by sequence similarity; putative.
  
     0.640
TM_1818
Chromate transport protein, putative; Similar to GB:AE000783 percent identity: 61.07; identified by sequence similarity; putative.
       0.559
TM_1819
Chromate transport protein, putative; Similar to PID:687689 percent identity: 55.06; identified by sequence similarity; putative.
       0.559
TM_1178
Acetyltransferase-related protein; Similar to GB:AE000657 percent identity: 50.40; identified by sequence similarity; putative.
  
     0.527
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
       0.493
psuG
Conserved hypothetical protein; Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Belongs to the pseudouridine-5'-phosphate glycosidase family.
      
 0.469
TM_0868
Glutaredoxin-related protein; Similar to PID:840852 percent identity: 68.35; identified by sequence similarity; putative.
  
     0.462
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.