STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aglAAlpha-glucosidase; Alpha-glycosidase with a very broad specificity. Hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch. AglA is not specific with respect to the configuration at the C-4 position of its substrates because glycosidic derivatives of D-galactose are also hydrolyzed. Does not cleave beta-glycosidic bonds. (480 aa)    
Predicted Functional Partners:
TM_0310
beta-D-galactosidase; Similar to GB:L03424 PID:551691 percent identity: 68.26; identified by sequence similarity; putative.
    
  0.991
galA
Alpha-galactosidase; Hydrolyzes the short-chain alpha-galactosaccharides raffinose, melibiose and stachyose.
    
  0.991
bfrA
Beta-fructosidase; Hydrolysis of sucrose, raffinose, inulin and levan. Specific for the fructose moiety and the beta-anomeric configuration of the glycosidic linkages of its substrates. The enzyme released fructose from sucrose and raffinose, and the fructose polymer inulin is hydrolyzed quantitatively in an exo-type fashion.
     
 0.991
TM_1195
Beta-galactosidase; Similar to GB:U08186 PID:473271 percent identity: 99.53; identified by sequence similarity; putative.
    
  0.986
lacZ
Beta-galactosidase; Similar to GB:U08186 PID:473272 GB:AE000512 percent identity: 99.61; identified by sequence similarity; putative.
    
  0.977
bglT
6-phospho-beta-glucosidase; Hydrolyzes cellobiose 6'-phosphate into glucose 6-phosphate (Glc6P) and glucose.
  
     0.772
aglB
Cyclomaltodextrinase, putative; Is able to hydrolyze various linear maltooligosaccharides (maltotriose to maltoheptaose) and cyclomaltodextrins (CDs), to mainly glucose and maltose, by liberating glucose from the reducing end of the molecules. Shows a very weak activity on starch. Can neither hydrolyze maltose nor degrade pullulan, but rapidly hydrolyzes acarbose, a strong amylase and glucosidase inhibitor, to acarviosine and glucose. Belongs to the glycosyl hydrolase 13 family.
    
 0.743
TM_1231
Alpha-mannosidase-related protein; Similar to SP:P21139 PID:205299 percent identity: 49.50; identified by sequence similarity; putative.
 
     0.650
TM_0229
Conserved hypothetical protein; Similar to GB:L77117 PID:1591686 percent identity: 52.10; identified by sequence similarity; putative.
  
     0.628
TM_0071
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; Similar to PID:1143602 percent identity: 84.56; identified by sequence similarity; putative.
  
     0.561
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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