Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
aglAAlpha-glucosidase; Alpha-glycosidase with a very broad specificity. Hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch. AglA is not specific with respect to the configuration at the C-4 position of its substrates because glycosidic derivatives of D-galactose are also hydrolyzed. Does not cleave beta-glycosidic bonds. (480 aa)    
Predicted Functional Partners:
bglT
6-phospho-beta-glucosidase; Hydrolyzes cellobiose 6'-phosphate into glucose 6-phosphate (Glc6P) and glucose.
  
     0.772
aglB
Cyclomaltodextrinase, putative; Is able to hydrolyze various linear maltooligosaccharides (maltotriose to maltoheptaose) and cyclomaltodextrins (CDs), to mainly glucose and maltose, by liberating glucose from the reducing end of the molecules. Shows a very weak activity on starch. Can neither hydrolyze maltose nor degrade pullulan, but rapidly hydrolyzes acarbose, a strong amylase and glucosidase inhibitor, to acarviosine and glucose. Belongs to the glycosyl hydrolase 13 family.
    
 0.691
TM_1231
Alpha-mannosidase-related protein; Similar to SP:P21139 PID:205299 percent identity: 49.50; identified by sequence similarity; putative.
 
     0.652
TM_0229
Conserved hypothetical protein; Similar to GB:L77117 PID:1591686 percent identity: 52.10; identified by sequence similarity; putative.
  
     0.628
TM_0071
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; Similar to PID:1143602 percent identity: 84.56; identified by sequence similarity; putative.
  
     0.561
TM_1833
Methyl-accepting chemotaxis-related protein; Similar to GB:L29189 SP:P39215 PID:459688 PID:1934800 GB:AL009126 percent identity: 51.14; identified by sequence similarity; putative.
       0.553
TM_0706
Hypothetical protein; Identified by sequence similarity; putative.
  
     0.550
TM_1199
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; Similar to PID:1652862 percent identity: 53.42; identified by sequence similarity; putative.
  
     0.525
TM_0300
Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, putative; Similar to GB:AE000657 percent identity: 48.20; identified by sequence similarity; putative.
  
     0.523
TM_1830
Conserved hypothetical protein; Similar to GB:AE000657 percent identity: 71.11; identified by sequence similarity; putative.
       0.508
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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