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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM_1878UDP-sugar hydrolase; Similar to SP:P07024 PID:757842 GB:U00096 PID:1773162 PID:1786687 percent identity: 62.97; identified by sequence similarity; putative; Belongs to the 5'-nucleotidase family. (508 aa)    
Predicted Functional Partners:
TM_0703
Competence-damage inducible protein, putative; Similar to GB:AL009126 percent identity: 61.61; identified by sequence similarity; putative; Belongs to the CinA family.
  
 
  0.997
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.995
TM_1596
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.995
TM_1737
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.995
tdk
Thymidine kinase; Similar to GB:U00089 SP:P75070 PID:1673767 percent identity: 57.80; identified by sequence similarity; putative.
 
  
  0.993
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.993
TM_0404
Deoxycytidylate deaminase, putative; Similar to GB:AE000782 percent identity: 74.00; identified by sequence similarity; putative.
 
 
  0.992
TM_0751
Uridine kinase-related protein; Similar to GB:U00089 SP:P75217 PID:1673952 percent identity: 52.11; identified by sequence similarity; putative.
  
 
 0.992
TM_0846
Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.992
purB
Adenylosuccinate lyase; Similar to GB:AE000657 percent identity: 73.60; identified by sequence similarity; putative.
  
 
 0.992
Your Current Organism:
Thermotoga maritima
NCBI taxonomy Id: 243274
Other names: T. maritima MSB8, Thermotoga maritima DSM 3109, Thermotoga maritima MSB8, Thermotoga maritima str. MSB8, Thermotoga maritima strain MSB8
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