node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
TDE_0454 | mfd | TDE_0454 | TDE_1287 | Conserved hypothetical protein; Identified by similarity to OMNI:VC1432; Belongs to the TtcA family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.645 |
TDE_0454 | pth | TDE_0454 | TDE_0643 | Conserved hypothetical protein; Identified by similarity to OMNI:VC1432; Belongs to the TtcA family. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.694 |
TDE_0644 | TDE_0645 | TDE_0644 | TDE_0645 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Conserved hypothetical protein. | 0.982 |
TDE_0644 | TDE_0646 | TDE_0644 | TDE_0646 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | Conserved hypothetical protein; Identified by similarity to SP:O83763. | 0.844 |
TDE_0644 | pth | TDE_0644 | TDE_0643 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.762 |
TDE_0645 | TDE_0644 | TDE_0645 | TDE_0644 | Conserved hypothetical protein. | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | 0.982 |
TDE_0645 | TDE_0646 | TDE_0645 | TDE_0646 | Conserved hypothetical protein. | Conserved hypothetical protein; Identified by similarity to SP:O83763. | 0.857 |
TDE_0645 | pth | TDE_0645 | TDE_0643 | Conserved hypothetical protein. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.762 |
TDE_0646 | TDE_0644 | TDE_0646 | TDE_0644 | Conserved hypothetical protein; Identified by similarity to SP:O83763. | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. | 0.844 |
TDE_0646 | TDE_0645 | TDE_0646 | TDE_0645 | Conserved hypothetical protein; Identified by similarity to SP:O83763. | Conserved hypothetical protein. | 0.857 |
TDE_0646 | pth | TDE_0646 | TDE_0643 | Conserved hypothetical protein; Identified by similarity to SP:O83763. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.762 |
mfd | TDE_0454 | TDE_1287 | TDE_0454 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Conserved hypothetical protein; Identified by similarity to OMNI:VC1432; Belongs to the TtcA family. | 0.645 |
mfd | polA | TDE_1287 | TDE_1637 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.688 |
mfd | pth | TDE_1287 | TDE_0643 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.784 |
mfd | tilS | TDE_1287 | TDE_1341 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.706 |
polA | mfd | TDE_1637 | TDE_1287 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.688 |
polA | prfA | TDE_1637 | TDE_2489 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.515 |
polA | priA | TDE_1637 | TDE_2490 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.471 |
polA | pth | TDE_1637 | TDE_0643 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.676 |
polA | ychF | TDE_1637 | TDE_0305 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.468 |