STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (260 aa)    
Predicted Functional Partners:
cobU
Cobinamide kinase/cobinamide phosphate guanyltransferase; Identified by similarity to SP:P46886; match to protein family HMM PF02283.
 
 
 0.997
TDE_2384
Identified by match to protein family HMM PF00300.
 
 
 0.988
cobO
cob(I)alamin adenosyltransferase; Identified by similarity to GP:151155; match to protein family HMM PF02572; match to protein family HMM TIGR00708.
 
 
 0.962
cobQ
Cobyric acid synthase CobQ, putative; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.957
cobT
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.921
cobJ
precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466.
  
  
 0.910
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.879
TDE_0624
precorrin-6X reductase, putative; Identified by similarity to GP:1926452; match to protein family HMM PF02571.
  
  
 0.842
TDE_1505
Membrane protein, putative.
   
    0.824
TDE_2657
Precorrin-2 C20-methyltransferase, putative; Identified by similarity to SP:Q05593; match to protein family HMM PF00590; Belongs to the precorrin methyltransferase family.
  
  
 0.767
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.