Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdR-1Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1039 aa)    
Predicted Functional Partners:
TDE_0368
Type I restriction-modification system, S subunit, putative; Identified by match to protein family HMM PF01420.
 
  
 0.983
hsdM-1
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497.
 
  
 0.981
TDE_0365
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM2291; match to protein family HMM PF01863.
 
   
 0.951
TDE_0367
Conserved hypothetical protein; Identified by similarity to OMNI:NMB0830.
  
    0.924
hsdM-2
Type I restriction-modification system, M subunit; Identified by similarity to SP:P08957; match to protein family HMM PF02384; match to protein family HMM PF02506.
 
  
 0.921
TDE_2740
Type I restriction-modification system, S subunit, truncation; Identified by match to protein family HMM PF01420.
 
  
 0.815
TDE_2743
Type I restriction-modification system, S subunit, truncation; Identified by match to protein family HMM PF01420.
 
  
 0.805
TDE_2550
Conserved hypothetical protein; Identified by similarity to GP:23325832; match to protein family HMM PF01863.
 
   
 0.789
hsdS
Type I restriction-modification system, S subunit; Identified by match to protein family HMM PF01420.
 
  
 0.771
TDE_1623
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01CJ01528; match to protein family HMM PF04373.
  
    0.738
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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