STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fabVConserved hypothetical protein; Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of the carbon-carbon double bond of crotonyl-CoA to yield butyryl-CoA. In vitro it can also use hexenoyl-CoA and dodecenoyl-CoA as substrates ; Belongs to the TER reductase family. (397 aa)    
Predicted Functional Partners:
TDE_0823
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase, putative; Identified by similarity to SP:P21774; match to protein family HMM PF03061.
  
 
 0.951
fabF
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.950
TDE_0595
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
TDE_0596
Conserved hypothetical protein.
       0.773
TDE_0601
Malonyl CoA-acyl carrier protein transacylase, putative; Identified by match to protein family HMM PF00698.
  
  
 0.693
TDE_0594
Cysteine protease domain, YopT-type.
       0.671
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
    0.641
TDE_2225
Identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051.
      
 0.621
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
      
 0.610
TDE_2512
Aldehyde dehydrogenase (NADP) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
      
 0.610
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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