Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TDE_1908Conserved hypothetical protein; Identified by similarity to OMNI:TP0827. (319 aa)    
Predicted Functional Partners:
dacA
Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
 
  
 0.957
acpS
Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.827
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
       0.792
TDE_2751
Conserved hypothetical protein; Identified by similarity to OMNI:TP0996.
  
     0.748
TDE_2607
Conserved hypothetical protein; Identified by similarity to OMNI:TP0333.
 
     0.732
TDE_1918
Conserved hypothetical protein; Identified by similarity to OMNI:BB0665.
 
     0.721
TDE_2293
Conserved hypothetical protein; Identified by similarity to OMNI:TP0408; match to protein family HMM TIGR01612; match to protein family HMM TIGR01967.
 
     0.720
TDE_2028
Identified by match to protein family HMM PF00691; match to protein family HMM TIGR01612.
  
     0.715
TDE_1732
Conserved hypothetical protein; Identified by similarity to OMNI:TP0843; match to protein family HMM PF00226.
 
     0.703
TDE_1092
Conserved hypothetical protein; Identified by similarity to OMNI:TP0990; match to protein family HMM PF00515; match to protein family HMM TIGR01612.
 
     0.693
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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