STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mafMaf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (203 aa)    
Predicted Functional Partners:
radC
DNA repair protein RadC; Identified by similarity to SP:P25531; match to protein family HMM PF04002; match to protein family HMM TIGR00608; Belongs to the UPF0758 family.
  
  
 0.852
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.753
TDE_2349
Conserved hypothetical protein; Identified by similarity to SP:O83617.
       0.743
TDE_2315
Conserved hypothetical protein TIGR00044; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
    0.695
TDE_0276
HD domain protein; Identified by match to protein family HMM PF01966.
 
      0.688
TDE_2619
RNA methyltransferase, TrmA family, putative; Identified by match to protein family HMM PF01938; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
     0.546
rpsB
Ribosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family.
  
    0.531
TDE_2350
Lipoprotein, putative; Identified by similarity to SP:O83516.
       0.491
flgK
Flagellar hook-associated protein FlgK; Identified by similarity to GP:1518046.
     
 0.473
TDE_1640
3-dehydroquinate dehydratase, type 1, putative/shikimate 5-dehydrogenase, putative; Identified by match to protein family HMM PF01487; match to protein family HMM PF01488.
     
 0.455
Your Current Organism:
Treponema denticola
NCBI taxonomy Id: 243275
Other names: T. denticola ATCC 35405, Treponema denticola ATCC 35405, Treponema denticola str. ATCC 35405
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