STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0014Predicted coding region TP0014; Hypothetical protein; identified by Glimmer; putative. (202 aa)    
Predicted Functional Partners:
TP_0013
Predicted coding region TP0013; Hypothetical protein; identified by Glimmer; putative.
     0.991
fliG2
Flagellar motor switch protein (fliG-2); FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
 
 0.814
ptsH
Phosphocarrier protein HPr (ptsH); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
   
 
 0.785
tprB
Tpr protein B (tprB); Similar to GP:2196926 percent identity: 37.13; identified by sequence similarity; putative.
       0.773
TP_0012
Predicted coding region TP0012; Hypothetical protein; identified by Glimmer; putative.
       0.773
pheT
phenylalanyl-tRNA synthetase beta subunit (pheT); Similar to GP:1785608 percent identity: 39.93; identified by sequence similarity; putative.
 
 
   0.734
TP_0010
Predicted coding region TP0010; Hypothetical protein; identified by Glimmer; putative.
       0.661
TP_0413
Phosphoglucomutase; Similar to GB:AE000783 percent identity: 35.60; identified by sequence similarity; putative.
  
 
  0.570
metG
methionyl-tRNA synthetase (metG); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
   0.566
tkt
Transketolase A (tktA); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
  0.553
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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