STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0017Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 36.16; identified by sequence similarity; putative. (315 aa)    
Predicted Functional Partners:
htpG
Heat shock protein 90 (htpG); Molecular chaperone. Has ATPase activity.
   
 0.958
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.954
alaS
alanyl-tRNA synthetase (alaS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).
   
  0.939
TP_0485
Adenylate cyclase; Similar to GP:1754638 percent identity: 40.99; identified by sequence similarity; putative.
   
  0.825
rpoA
DNA-directed RNA polymerase, alpha subunit (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.754
TP_0563
Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative.
    
  0.739
TP_0018
Transcription elongation factor; Similar to GB:AE000783 percent identity: 33.20; identified by sequence similarity; putative.
       0.701
TP_0502
Predicted coding region TP0502; Hypothetical protein; identified by Glimmer; putative.
   
  0.682
TP_0597
Predicted coding region TP0597; Hypothetical protein; identified by Glimmer; putative.
    
  0.682
TP_0598
Predicted coding region TP0598; Hypothetical protein; identified by Glimmer; putative.
    
  0.682
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.