STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_002076K protein; Similar to GP:2108236 percent identity: 99.56; identified by sequence similarity; putative. (707 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor (greA); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.803
TP_0289
Predicted coding region TP0289; Hypothetical protein; identified by Glimmer; putative.
   
 0.750
TP_0245
Predicted coding region TP0245; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.608
TP_0018
Transcription elongation factor; Similar to GB:AE000783 percent identity: 33.20; identified by sequence similarity; putative.
       0.534
TP_0017
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 36.16; identified by sequence similarity; putative.
       0.525
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
  0.493
TP_0421
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.26; identified by sequence similarity; putative.
    
  0.477
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
   
 
  0.455
TP_0433
Predicted coding region TP0433; Hypothetical protein; identified by Glimmer; putative.
    
  0.401
TP_0434
Predicted coding region TP0434; Hypothetical protein; identified by Glimmer; putative.
    
  0.401
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.