STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0024Conserved hypothetical protein; Similar to GB:D37799 SP:P39760 PID:520844 PID:1377829 GB:AL009126 percent identity: 30.32; identified by sequence similarity; putative. (236 aa)    
Predicted Functional Partners:
TP_0140
K+ transport protein (ntpJ); Similar to GP:2635594 percent identity: 37.01; identified by sequence similarity; putative.
 
 
 0.990
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
  
 
  0.830
flgG2
Flagellar basal-body rod protein (flgG-2); Similar to GB:AE000783 percent identity: 50.37; identified by sequence similarity; putative.
    
   0.769
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.698
TP_0876
Conserved hypothetical protein; Similar to GB:U00096 SP:P76256 PID:1736440 PID:1736446 PID:1788109 percent identity: 32.58; identified by sequence similarity; putative.
   
 
 0.466
TP_0023
Sodium- and chloride- dependent transporter; Similar to GB:L77117 SP:Q58715 PID:1591959 percent identity: 29.44; identified by sequence similarity; putative.
       0.455
nadK
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
  0.448
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity).
   
   0.437
TP_0563
Predicted coding region TP0563; Hypothetical protein; identified by Glimmer; putative.
   
 
 0.435
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
  0.430
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.