STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0047Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.47; identified by sequence similarity; putative. (173 aa)    
Predicted Functional Partners:
tpl
Hypothetical protein; Supposed to have signal peptidase II-like activity.
  
  
 0.925
TP_0048
Conserved hypothetical protein; Similar to PID:1017747 PID:1372995 GB:AE000783 percent identity: 27.08; identified by sequence similarity; putative.
     
 0.910
TP_0049
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 50.57; identified by sequence similarity; putative.
       0.812
fliS
Flagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative.
  
 
 0.658
TP_0989
P26; Similar to GB:AE000783 percent identity: 31.90; identified by sequence similarity; putative.
  
 
   0.633
TP_0050
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 41.88; identified by sequence similarity; putative.
 
   
 0.603
ftsQ
Cell division protein (ftsQ); Essential cell division protein.
  
     0.601
TP_0996
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 30.00; identified by sequence similarity; putative.
  
     0.554
TP_0408
Predicted coding region TP0408; Hypothetical protein; identified by Glimmer; putative.
 
     0.526
def
Polypeptide deformylase (def); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
   
   0.488
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.