STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0048Conserved hypothetical protein; Similar to PID:1017747 PID:1372995 GB:AE000783 percent identity: 27.08; identified by sequence similarity; putative. (143 aa)    
Predicted Functional Partners:
TP_0047
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.47; identified by sequence similarity; putative.
     
 0.910
tpl
Hypothetical protein; Supposed to have signal peptidase II-like activity.
     
 0.897
fliS
Flagellar protein (fliS); Similar to GB:Z31376 SP:P39739 PID:499382 PID:1762346 GB:AL009126 percent identity: 34.48; identified by sequence similarity; putative.
    
 
 0.877
TP_0049
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 50.57; identified by sequence similarity; putative.
       0.794
fliY
Flagellar motor switch protein (fliY); FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
    
   0.769
TP_0267
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.59; identified by sequence similarity; putative.
  
     0.742
TP_0253
Conserved hypothetical protein; Similar to PID:1017747 PID:1372995 GB:AE000783 percent identity: 29.51; identified by sequence similarity; putative.
  
     0.690
rsmG
Glucose-inhibited division protein B (gidB); Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
   
 
 0.685
rpe
Ribulose-phosphate 3-epimerase (cfxE); Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.
    
 
 0.681
macA
Membrane fusion protein, putative; Similar to GB:L42023 PID:1005989 PID:1220998 PID:1205141 SP:Q57500 percent identity: 25.88; identified by sequence similarity; putative.
 
 
   0.503
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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