STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0049Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 50.57; identified by sequence similarity; putative. (342 aa)    
Predicted Functional Partners:
TP_0048
Conserved hypothetical protein; Similar to PID:1017747 PID:1372995 GB:AE000783 percent identity: 27.08; identified by sequence similarity; putative.
       0.794
TP_0047
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.47; identified by sequence similarity; putative.
       0.779
tpl
Hypothetical protein; Supposed to have signal peptidase II-like activity.
       0.761
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
  
 
 0.475
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
  0.455
fliM
Flagellar motor switch protein (fliM); FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
    
   0.449
add
Adenosine deaminase, putative; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
 
     0.441
mrcA
Penicillin-binding protein (pbp-2); Similar to GB:AE000783 percent identity: 40.76; identified by sequence similarity; putative.
  
     0.428
TP_0050
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 41.88; identified by sequence similarity; putative.
       0.408
dacC
Serine-type D-Ala-D-Ala carboxypeptidase (dacC); Similar to GB:AE000783 percent identity: 30.68; identified by sequence similarity; putative; Belongs to the peptidase S11 family.
  
 
  0.403
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.