STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpsRRibosomal protein S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (99 aa)    
Predicted Functional Partners:
rplI
Ribosomal protein L9 (rplI); Binds to the 23S rRNA.
 
 
 0.998
rpsF
Ribosomal protein S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
  
 
 0.997
rpsC
Ribosomal protein S3 (rpsC); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.996
rpmB
Ribosomal protein L28 (rpmB); Similar to GP:1763103 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.996
rpsB
Ribosomal protein S2 (rpsB); Similar to GB:AE000783 percent identity: 58.75; identified by sequence similarity; putative; Belongs to the universal ribosomal protein uS2 family.
  
 0.996
rpsO
Ribosomal protein S15 (rpsO); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
 0.996
rpsQ
Ribosomal protein S17 (rpsQ); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 0.995
rpsZ
Ribosomal protein S14 (rpsN); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.995
cmk
Ribosomal protein S1 (rpsA); Similar to SP:P02349 GB:V00342 GB:V00352 GB:X04864 PID:42837 percent identity: 36.77; identified by sequence similarity; putative.
  
 0.994
rpmG
Ribosomal protein L33 (rpmG); Similar to SP:P35871 percent identity: 60.87; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL33 family.
  
 
 0.993
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.