STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0065Conserved hypothetical protein; Similar to GP:1694865 percent identity: 36.11; identified by sequence similarity; putative. (195 aa)    
Predicted Functional Partners:
coaD
Lipopolysaccharide core biosynthesis protein (kdtB); Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.900
TP_0066
Predicted coding region TP0066; Hypothetical protein; identified by Glimmer; putative.
       0.831
TP_0067
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 47.91; identified by sequence similarity; putative.
       0.827
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
       0.580
TP_0064
Predicted coding region TP0064; Hypothetical protein; identified by Glimmer; putative.
       0.565
polA
DNA polymerase I (polA); In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.544
ftsY
Cell division protein (ftsY); Similar to SP:P51835 percent identity: 38.16; identified by sequence similarity; putative.
     
 0.434
recJ
single-stranded-DNA-specific exonuclease (recJ); Similar to GB:AE000783 percent identity: 24.42; identified by sequence similarity; putative.
  
    0.424
der
GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
    0.418
TP_0694
5,10-methenyltetrahydrofolate synthetase, putative; Similar to GB:L38928 SP:P49914 PID:886297 percent identity: 30.69; identified by sequence similarity; putative.
     
 0.418
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.