STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0078Spore coat polysaccharide biosynthesis protein (spsC); Similar to GB:X73124 SP:P39623 PID:413989 GB:AL009126 percent identity: 40.58; identified by sequence similarity; putative; Belongs to the DegT/DnrJ/EryC1 family. (412 aa)    
Predicted Functional Partners:
capD
Capsular polysaccharide biosynthesis protein (cap5D); Similar to GP:1773343 percent identity: 42.49; identified by sequence similarity; putative.
  
 
 0.994
TP_0289
Predicted coding region TP0289; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.930
spsE
Spore coat polysaccharide biosynthesis protein (spsE); Similar to GB:X73124 SP:P39625 PID:413991 GB:AL009126 percent identity: 27.64; identified by sequence similarity; putative.
 
  
 0.876
coxL
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 26.11; identified by sequence similarity; putative.
       0.836
coxS
Quinoline 2-oxidoreductase; Similar to GP:1644310 percent identity: 30.34; identified by sequence similarity; putative.
       0.836
coxM
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 26.50; identified by sequence similarity; putative.
  
    0.832
fmt
methionyl-tRNA formyltransferase (fmt); Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
 
 0.736
wecE
Spore coat polysaccharide biosynthesis protein, putative; Similar to PID:1653135 percent identity: 23.08; identified by sequence similarity; putative; Belongs to the DegT/DnrJ/EryC1 family.
  
     0.709
TP_0076
Sugar ABC transporter, permease protein (y4oR); Similar to SP:P55603 PID:2182562 percent identity: 35.38; identified by sequence similarity; putative.
       0.639
TP_0288
Spore coat polysaccharide biosynthesis protein (spsF); Similar to GB:X73124 SP:P39626 PID:413992 GB:AL009126 percent identity: 31.88; identified by sequence similarity; putative.
 
  
 0.632
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.