STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0085PTS system, nitrogen regulatory IIA component (ptsN-1); Similar to GB:X16474 SP:P33670 PID:405792 percent identity: 26.35; identified by sequence similarity; putative. (148 aa)    
Predicted Functional Partners:
ptsN
PTS system, nitrogen regulatory IIA component (ptsN-2); Similar to GB:D12938 SP:P31222 GB:Z27094 PID:285783 PID:414887 percent identity: 29.86; identified by sequence similarity; putative.
  
  
 
0.941
gph
Phosphoglycolate phosphatase (gph-2); Similar to GB:L42023 SP:P44755 PID:1004013 PID:1222502 PID:1204815 percent identity: 32.55; identified by sequence similarity; putative.
   
  0.613
ptsH
Phosphocarrier protein HPr (ptsH); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.610
fba
Fructose-bisphosphate aldolase (cbbA); Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.583
TP_0086
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 22.86; identified by sequence similarity; putative.
       0.551
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
     
 0.536
TP_0084
Predicted coding region TP0084; Hypothetical protein; identified by Glimmer; putative.
       0.511
ackA
Acetate kinase (ack); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
    0.485
TP_0461
Predicted coding region TP0461; Hypothetical protein; identified by Glimmer; putative.
     
  0.457
TP_0505
Hexokinase (hxk); Similar to SP:Q09756 percent identity: 27.15; identified by sequence similarity; putative.
     
  0.457
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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