STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoERNA polymerase sigma-24 factor (rpoE); Similar to PID:699142 percent identity: 27.89; identified by sequence similarity; putative. (162 aa)    
Predicted Functional Partners:
TP_0093
Predicted coding region TP0093; Hypothetical protein; identified by Glimmer; putative.
  
 
 0.994
rpoA
DNA-directed RNA polymerase, alpha subunit (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.946
rpoB
DNA-directed RNA polymerase, beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.946
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.946
rpoZ
DNA-directed RNA polymerase, putative; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
    
 
 0.946
TP_0990
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 23.34; identified by sequence similarity; putative.
   
   0.928
cheR
Chemotaxis protein methyltransferase (cheR); Similar to GB:AE000783 percent identity: 47.10; identified by sequence similarity; putative.
    
   0.880
fliG2
Flagellar motor switch protein (fliG-2); FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
    
 
 0.782
fliI
Flagellum-specific ATP synthase (fliI); Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.
    
 
 0.772
fliE
Flagellar hook-basal body complex protein (fliE); Similar to GP:2105147 percent identity: 58.12; identified by sequence similarity; putative.
    
   0.769
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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