STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptaPhosphate acetyltransferase (pta); Similar to GB:L23147 SP:P38503 PID:349833 percent identity: 42.30; identified by sequence similarity; putative. (336 aa)    
Predicted Functional Partners:
ackA
Acetate kinase (ack); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.998
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
 0.994
oadA
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 50.93; identified by sequence similarity; putative.
    
 0.970
ldhD
D-specific D-2-hydroxyacid dehydrogenase; Similar to GP:1644433 percent identity: 42.48; identified by sequence similarity; putative.
   
 0.916
ppdK
Pyruvate, phosphate dikinase; Catalyzes the reversible phosphorylation of pyruvate and phosphate; Belongs to the PEP-utilizing enzyme family.
    
 0.856
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
  
 0.828
TP_0095
Predicted coding region TP0095; Hypothetical protein; identified by Glimmer; putative.
       0.773
TP_0291
Predicted coding region TP0291; Hypothetical protein; identified by Glimmer; putative.
     
 0.750
gpmA
Phosphoglycerate mutase (pgm); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.748
oadB
Oxaloacetate decarboxylase, subunit beta (oadB); Similar to GB:M96434 SP:Q03031 PID:154198 percent identity: 61.56; identified by sequence similarity; putative.
     
 0.738
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: low (26%) [HD]