STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0107licC protein (licC); Similar to GB:L42023 PID:1007733 PID:1221685 PID:1205774 PID:1574381 percent identity: 29.03; identified by sequence similarity; putative. (525 aa)    
Predicted Functional Partners:
TP_0106
Carnitine transporter, putative; Similar to GB:D10483 SP:P31553 GB:X73904 PID:216465 PID:563861 percent identity: 30.04; identified by sequence similarity; putative; Belongs to the BCCT transporter (TC 2.A.15) family.
 
     0.957
folD
Methylenetetrahydrofolate dehydrogenase (folD); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
   
 
  0.815
TP_0986
Conserved hypothetical integral membrane protein; Similar to GB:AE000511 PID:2314395 percent identity: 30.69; identified by sequence similarity; putative.
  
  
 0.698
ispDF
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
     
 0.680
TP_0572
Predicted coding region TP0572; Hypothetical protein; identified by Glimmer; putative.
  
     0.640
pdxK
Phosphomethypyrimidine kinase (thiD); Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates (By similarity); Belongs to the ThiD family.
     
 0.635
glpQ
Glycerophosphoryldiester phosphodiesterase (glpQ); Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
    
 0.606
murC
UDP-N-acetylmuramate--alanine ligase (murC); Cell wall formation; Belongs to the MurCDEF family.
    
  0.573
pgsA2
Conserved hypothetical protein; Similar to PID:2088865 percent identity: 28.12; identified by sequence similarity; putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
   
 0.553
folC
Folylpolyglutamate synthetase (folC); Similar to GB:L04520 SP:Q05865 PID:142936 PID:1119198 GB:AL009126 percent identity: 35.29; identified by sequence similarity; putative.
     
 0.498
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.