STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflCLambda CII stability-governing protein (hflC); HflC and HflK could regulate a protease. (331 aa)    
Predicted Functional Partners:
hflK
Lambda CII stability-governing protein (hflK); HflC and HflK could encode or regulate a protease.
 
   
 0.981
ftsH
Cell division protein (ftsH); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.
   
 0.955
cheW1
Purine-binding chemotaxis protein (cheW-1); Similar to GP:1765974 percent identity: 99.78; identified by sequence similarity; putative.
    
  0.866
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.804
TP_0982
glpG protein, putative; Similar to GP:606359 percent identity: 29.47; identified by sequence similarity; putative.
   
 0.793
tuf
Translation elongation factor TU (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.639
yidC
Membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
 
 0.637
cheB
Protein-glutamate methylesterase (cheB); Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
  0.621
TP_0815
Predicted coding region TP0815; Hypothetical protein; identified by Glimmer; putative.
  
    0.542
pepC
Aminopeptidase C (pepC); Similar to GB:Z30315 PID:535273 percent identity: 44.59; identified by sequence similarity; putative; Belongs to the peptidase C1 family.
  
    0.527
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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