STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pckGPhosphoenolpyruvate carboxykinase (pckA); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP); Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (618 aa)    
Predicted Functional Partners:
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
 
 0.997
ppdK
Pyruvate, phosphate dikinase; Catalyzes the reversible phosphorylation of pyruvate and phosphate; Belongs to the PEP-utilizing enzyme family.
     
 0.963
oadA
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 50.93; identified by sequence similarity; putative.
     
 0.949
oadB
Oxaloacetate decarboxylase, subunit beta (oadB); Similar to GB:M96434 SP:Q03031 PID:154198 percent identity: 61.56; identified by sequence similarity; putative.
     
 0.937
eno
Enolase (eno); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.934
gltD
Glutamate synthase (gltA); Similar to GP:2244618 percent identity: 48.79; identified by sequence similarity; putative.
   
 
  0.922
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
  
 
 0.802
nadE
NH(3)-dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.
   
 
  0.704
ldhD
D-specific D-2-hydroxyacid dehydrogenase; Similar to GP:1644433 percent identity: 42.48; identified by sequence similarity; putative.
     
 0.703
TP_0055
Predicted coding region TP0055; Hypothetical protein; identified by Glimmer; putative.
     
  0.690
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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