STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0140K+ transport protein (ntpJ); Similar to GP:2635594 percent identity: 37.01; identified by sequence similarity; putative. (575 aa)    
Predicted Functional Partners:
TP_0139
Conserved hypothetical protein; Similar to GB:D37799 SP:P39760 PID:520844 PID:1377829 GB:AL009126 percent identity: 39.78; identified by sequence similarity; putative.
 
 
 0.996
TP_0024
Conserved hypothetical protein; Similar to GB:D37799 SP:P39760 PID:520844 PID:1377829 GB:AL009126 percent identity: 30.32; identified by sequence similarity; putative.
 
 
 0.990
trkA
K+ transport protein (trkA); Similar to SP:P23868 GB:X52114 PID:43137 PID:443993 PID:606224 percent identity: 23.86; identified by sequence similarity; putative.
  
 
 0.949
TP_0138
Predicted coding region TP0138; Hypothetical protein; identified by Glimmer; putative.
       0.738
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
 
 0.599
ada
methylated-DNA-protein-cysteine S-methyltransferase (dat); Similar to SP:P11742 GB:X15659 PID:39876 GB:AL009126 percent identity: 38.46; identified by sequence similarity; putative.
       0.526
TP_0840
Conserved hypothetical integral membrane protein; Similar to GB:AE000782 percent identity: 25.96; identified by sequence similarity; putative.
     
 0.512
fmt
methionyl-tRNA formyltransferase (fmt); Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
  
 0.453
TP_0028
Hemolysin, putative; Similar to PID:1653594 percent identity: 26.34; identified by sequence similarity; putative.
     
 0.449
proA
Glutamate-5-semialdehyde dehydrogenase (proA); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
 0.436
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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