STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnfDConserved hypothetical integral membrane protein; Similar to GP:1787917 percent identity: 29.71; identified by sequence similarity; putative. (339 aa)    
Predicted Functional Partners:
rnfC
Nitrogen fixation protein (rnfC); Similar to GB:X72888 GB:X79064 PID:435525 PID:483572 PID:1905810 percent identity: 27.00; identified by sequence similarity; putative.
  
 
 0.999
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
   
 
 0.990
TP_0147
Alpha-amylase 1, putative; Similar to SP:P09961 PID:2689 percent identity: 27.92; identified by sequence similarity; putative.
     
 0.892
TP_0149
Predicted coding region TP0149; Hypothetical protein; identified by Glimmer; putative.
     
 0.887
TP_0153
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 37.67; identified by sequence similarity; putative.
     
 0.834
TP_0150
Predicted coding region TP0150; Hypothetical protein; identified by Glimmer; putative.
     
 0.825
TP_0148
Predicted coding region TP0148; Hypothetical protein; identified by Glimmer; putative.
     
 0.812
TP_0572
Predicted coding region TP0572; Hypothetical protein; identified by Glimmer; putative.
     
 0.722
apbE
Conserved hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein (By similarity). Displays FAD pyrophosphatase activity in vitro, hydrolyzing FAD into FMN and AMP.
  
  
 0.632
nth
Endonuclease III (nth); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 0.497
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.