STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
troAABC transporter, periplasmic binding protein (troA); Part of an ATP-driven transport system TroABCD for zinc. Substrate-binding protein involved in the transport of zinc across the cytoplasmic membrane. (308 aa)    
Predicted Functional Partners:
troB
ABC transporter, ATP-binding protein (troB); Part of an ATP-driven transport system TroABCD for zinc.
 
 
 0.999
troC
ABC transporter, permease protein (troC); Part of an ATP-driven transport system TroABCD for zinc; Belongs to the ABC-3 integral membrane protein family.
 
 0.999
troD
ABC transporter, permease protein (troD); Part of an ATP-driven transport system TroABCD for zinc; Belongs to the ABC-3 integral membrane protein family.
 
 0.998
TP_0035
ABC transporter, ATP-binding protein; Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.
  
 
 0.970
troR
Cation-activated repressor protein (troR); Similar to GP:1777937 percent identity: 100.00; identified by sequence similarity; putative.
  
 
 0.921
TP_0036
ABC transporter, permease protein; Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal; Belongs to the ABC-3 integral membrane protein family.
  
 
 0.898
gpmA
Phosphoglycerate mutase (pgm); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
 0.742
rpmB
Ribosomal protein L28 (rpmB); Similar to GP:1763103 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.680
rpsZ
Ribosomal protein S14 (rpsN); Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.674
ruvB
Holliday junction DNA helicase (ruvB); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.550
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.