STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
troDABC transporter, permease protein (troD); Part of an ATP-driven transport system TroABCD for zinc; Belongs to the ABC-3 integral membrane protein family. (367 aa)    
Predicted Functional Partners:
troB
ABC transporter, ATP-binding protein (troB); Part of an ATP-driven transport system TroABCD for zinc.
 
 0.999
troA
ABC transporter, periplasmic binding protein (troA); Part of an ATP-driven transport system TroABCD for zinc. Substrate-binding protein involved in the transport of zinc across the cytoplasmic membrane.
 
 0.998
troC
ABC transporter, permease protein (troC); Part of an ATP-driven transport system TroABCD for zinc; Belongs to the ABC-3 integral membrane protein family.
 
  
0.993
TP_0035
ABC transporter, ATP-binding protein; Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.
  
 0.968
troR
Cation-activated repressor protein (troR); Similar to GP:1777937 percent identity: 100.00; identified by sequence similarity; putative.
  
 
 0.950
TP_0034
ABC transporter, periplasmic binding protein; Part of an ATP-driven transport system TP_0034/TP_0035/TP_0036 for a metal. Metal-binding component; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.907
gpmA
Phosphoglycerate mutase (pgm); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.865
TP_0804
Sugar ABC transporter, ATP-binding protein (ugpC); Similar to SP:P10907 GB:U00039 PID:43249 PID:912455 GB:U00096 percent identity: 47.77; identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
    
  0.470
proS
prolyl-tRNA synthetase (proS); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and invol [...]
  
    0.464
lolD
ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 
 0.413
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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