STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpp15Lipoprotein, 15 kDa (tpp15); Similar to GB:M30941 SP:P16055 PID:155073 PID:1777940 percent identity: 97.12; identified by sequence similarity; putative. (142 aa)    
Predicted Functional Partners:
apbE
Conserved hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein (By similarity). Displays FAD pyrophosphatase activity in vitro, hydrolyzing FAD into FMN and AMP.
 
   
 0.813
TP_0348
Predicted coding region TP0348; Hypothetical protein; identified by Glimmer; putative.
 
     0.674
tpd
Membrane antigen, pathogen-specific (tpd); This antigen is a pathogen-specific membrane immunogen; Belongs to the UPF0423 family.
   
 
 0.638
tpf1
Bacterioferrin (TpF1); May play an important structural role in the outer membrane; Belongs to the Dps family.
    
 
 0.561
TP_1032
Predicted coding region TP1032; Hypothetical protein; identified by Glimmer; putative.
   
   0.536
TP_0169
Predicted coding region TP0169; Hypothetical protein; identified by Glimmer; putative.
       0.526
mtnN
Pfs protein (pfs); Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
       0.526
rnfC
Nitrogen fixation protein (rnfC); Similar to GB:X72888 GB:X79064 PID:435525 PID:483572 PID:1905810 percent identity: 27.00; identified by sequence similarity; putative.
  
   
 0.502
tpp17
Lipoprotein, 17 kDa (tpp17); Similar to GB:M74825 SP:P29722 PID:155048 percent identity: 100.00; identified by sequence similarity; putative.
      
 0.487
ruvB
Holliday junction DNA helicase (ruvB); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
   0.481
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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