STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0221D,D-carboxypeptidase, putative; Similar to GB:AE000783 percent identity: 36.45; identified by sequence similarity; putative. (260 aa)    
Predicted Functional Partners:
dacC
Serine-type D-Ala-D-Ala carboxypeptidase (dacC); Similar to GB:AE000783 percent identity: 30.68; identified by sequence similarity; putative; Belongs to the peptidase S11 family.
     
 0.940
TP_0220
Anti-sigma F factor antagonist (spoIIAA-1); Similar to GB:M25260 SP:P26777 PID:304171 percent identity: 29.35; identified by sequence similarity; putative; Belongs to the anti-sigma-factor antagonist family.
       0.789
TP_0222
Predicted coding region TP0222; Hypothetical protein; identified by Glimmer; putative.
       0.762
rsbU1
Sigma factor SigB regulation protein, putative; Similar to GP:1934988 percent identity: 26.36; identified by sequence similarity; putative.
       0.680
rsbU2
Sigma factor SigG regulation protein, putative; Similar to SP:P40399 PID:1146194 PID:1881280 PID:1881280 GB:AL009126 percent identity: 22.82; identified by sequence similarity; putative.
       0.680
deoD
Purine nucleoside phosphorylase (deoD); Similar to GP:1638807 percent identity: 57.51; identified by sequence similarity; putative.
  
    0.539
pbp1
Penicillin-binding protein (pbp-1); Similar to GB:AE000783 percent identity: 37.14; identified by sequence similarity; putative.
     
 0.514
pbp2
Penicillin-binding protein (pbp-3); Similar to GB:AE000783 percent identity: 30.81; identified by sequence similarity; putative.
     
 0.514
ddl
D-alanine--D-alanine ligase (ddlA); Cell wall formation.
 
   
 0.491
alr
Alanine racemase (alr); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.433
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.