STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0225Leucine-rich repeat protein TpLRR; Similar to GP:2104502 percent identity: 100.00; identified by sequence similarity; putative. (246 aa)    
Predicted Functional Partners:
TP_0223
Aspartate aminotransferase (tpaaT); Similar to GP:2104501 percent identity: 99.77; identified by sequence similarity; putative.
    
  0.735
TP_0224
Predicted coding region TP0224; Hypothetical protein; identified by Glimmer; putative.
       0.625
oadA
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 50.93; identified by sequence similarity; putative.
  
    0.550
TP_0911
Conserved hypothetical protein; Similar to GB:AL009126 percent identity: 35.14; identified by sequence similarity; putative.
   
  
 0.546
TP_0854
Predicted coding region TP0854; Hypothetical protein; identified by Glimmer; putative.
      
 0.509
TP_0484
Predicted coding region TP0484; Hypothetical protein; identified by Glimmer; putative.
  
   0.505
TP_0593
Predicted coding region TP0593; Hypothetical protein; identified by Glimmer; putative.
  
   0.505
TP_0711
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.11; identified by sequence similarity; putative.
  
   0.505
secD
Protein-export membrane protein (secD); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
    
  0.433
TP_0546
Periplasmic serine protease, putative; Similar to GB:L20127 PID:310329 percent identity: 37.30; identified by sequence similarity; putative.
    
 0.408
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.