STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bioYBiotin synthase, putative; Probable biotin transporter; Belongs to the BioY family. (271 aa)    
Predicted Functional Partners:
cbiO
Cobalt ABC transporter, ATP-binding protein; Similar to GB:L77117 PID:1591732 percent identity: 37.91; identified by sequence similarity; putative.
 
 
 0.998
TP_0838
ABC transporter, ATP-binding protein; Similar to PID:1027507 GB:AE000783 percent identity: 58.04; identified by sequence similarity; putative.
    
  0.722
birA
biotin--acetyl-CoA-carboxylase ligase (birA); Similar to GP:1877334 percent identity: 28.89; identified by sequence similarity; putative.
 
   
 0.684
udg
DNA polymerase, bacteriophage-type; Similar to GB:AE000782 percent identity: 44.38; identified by sequence similarity; putative.
       0.572
priA
Primosomal protein N (priA); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.572
oadA
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 50.93; identified by sequence similarity; putative.
     
 0.499
TP_0226
Predicted coding region TP0226; Hypothetical protein; identified by Glimmer; putative.
       0.469
TP_0231
Conserved hypothetical protein; Similar to PID:882688 GB:U00096 SP:Q46918 PID:1789155 PID:882686 percent identity: 36.22; identified by sequence similarity; putative.
       0.401
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.