STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
udgDNA polymerase, bacteriophage-type; Similar to GB:AE000782 percent identity: 44.38; identified by sequence similarity; putative. (277 aa)    
Predicted Functional Partners:
priA
Primosomal protein N (priA); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.837
oadA
Oxaloacetate decarboxylase, subunit alpha (oadA); Similar to GB:J03885 SP:P13187 PID:149289 percent identity: 50.93; identified by sequence similarity; putative.
  
    0.815
TP_0876
Conserved hypothetical protein; Similar to GB:U00096 SP:P76256 PID:1736440 PID:1736446 PID:1788109 percent identity: 32.58; identified by sequence similarity; putative.
  
    0.754
gpmA
Phosphoglycerate mutase (pgm); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.662
bioY
Biotin synthase, putative; Probable biotin transporter; Belongs to the BioY family.
       0.572
TP_0231
Conserved hypothetical protein; Similar to PID:882688 GB:U00096 SP:Q46918 PID:1789155 PID:882686 percent identity: 36.22; identified by sequence similarity; putative.
  
    0.572
flgC
Flagellar basal-body rod protein (flgC); Similar to GP:2105146 percent identity: 67.11; identified by sequence similarity; putative.
    
   0.557
ssb
Single-strand DNA binding protein (ssb); Similar to GB:AE000783 percent identity: 48.15; identified by sequence similarity; putative.
   
   0.510
ssb2
Predicted coding region TP0310; Hypothetical protein; identified by Glimmer; putative.
   
   0.510
TP_0438
Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.495
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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