STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
flaAFlagellar filament outer layer protein (flaA-1); Component of the outer layer of the flagella. (350 aa)    
Predicted Functional Partners:
flaB1
Flagellar filament 34.5 kDa core protein (flaB1); Component of the core of the flagella.
      
 0.749
flaB2
Flagellar filament 33 kDa core protein (flaB2); Component of the core of the flagella.
      
 0.723
flgE
Flagellar hook protein (flgE); Similar to GP:2196893 percent identity: 100.00; identified by sequence similarity; putative.
      
 0.695
TP_0248
Predicted coding region TP0248; Hypothetical protein; identified by Glimmer; putative.
     
 0.689
amiC
N-acetylmuramoyl-L-alanine amidase (amiA); Similar to SP:P36548 GB:X75413 PID:453968 GB:U00096 PID:1788776 percent identity: 30.74; identified by sequence similarity; putative.
       0.624
TP_0250
Predicted coding region TP0250; Hypothetical protein; identified by Glimmer; putative.
       0.613
flaB3
Flagellar filament 31 kDa core protein (flaB3); Component of the core of the flagella.
      
 0.575
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.486
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
Server load: medium (52%) [HD]