STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0259Predicted coding region TP0259; Hypothetical protein; identified by Glimmer; putative. (203 aa)    
Predicted Functional Partners:
TP_0258
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 33.52; identified by sequence similarity; putative.
       0.552
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
    
  0.490
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.488
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
  0.473
TP_0624
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 21.58; identified by sequence similarity; putative.
  
 
  0.473
TP_0751
Predicted coding region TP0751; Hypothetical protein; identified by Glimmer; putative.
  
 
  0.473
mazG
mazG protein (mazG); Similar to GB:J04039 SP:P33646 PID:416198 PID:882675 GB:U00096 percent identity: 37.45; identified by sequence similarity; putative.
    
  0.455
TP_0484
Predicted coding region TP0484; Hypothetical protein; identified by Glimmer; putative.
   
   0.454
TP_0593
Predicted coding region TP0593; Hypothetical protein; identified by Glimmer; putative.
   
   0.454
TP_0711
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 27.11; identified by sequence similarity; putative.
   
   0.454
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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