STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TP_0259Predicted coding region TP0259; Hypothetical protein; identified by Glimmer; putative. (203 aa)    
Predicted Functional Partners:
TP_0258
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 33.52; identified by sequence similarity; putative.
       0.552
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
     
 0.525
tpf1
Bacterioferrin (TpF1); May play an important structural role in the outer membrane; Belongs to the Dps family.
   
    0.517
TP_0623
Membrane-bound lytic murein transglycosylase D (dniR); Similar to SP:P23931 GB:X60739 PID:1208972 PID:581068 GB:U00096 percent identity: 32.28; identified by sequence similarity; putative.
    
 0.487
TP_0592
Predicted coding region TP0592; Hypothetical protein; identified by Glimmer; putative.
   
 
 0.430
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.423
tpn50
Outer membrane protein (tpn50); Could function as a porin; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
  0.404
TP_0624
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 21.58; identified by sequence similarity; putative.
  
 
  0.404
TP_0751
Predicted coding region TP0751; Hypothetical protein; identified by Glimmer; putative.
  
 
  0.404
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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