STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP_0261Catabolite gene activator, putative; Similar to PID:1653345 percent identity: 30.99; identified by sequence similarity; putative. (347 aa)    
Predicted Functional Partners:
TP_0485
Adenylate cyclase; Similar to GP:1754638 percent identity: 40.99; identified by sequence similarity; putative.
 
 0.994
TP_0939
Pyruvate oxidoreductase; Similar to PID:1001780 SP:P52965 PID:1006618 percent identity: 58.44; identified by sequence similarity; putative.
  
 
 0.977
ndk
Nucleoside-diphosphate kinase (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
  0.976
dnaK
Heat shock protein 70 (dnaK); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.968
TP_0502
Predicted coding region TP0502; Hypothetical protein; identified by Glimmer; putative.
 
 0.960
TP_0835
Ankyrin, putative; Similar to GB:X56958 SP:Q01485 PID:29491 percent identity: 30.66; identified by sequence similarity; putative.
 
 0.960
TP_0597
Predicted coding region TP0597; Hypothetical protein; identified by Glimmer; putative.
   
 0.954
TP_0598
Predicted coding region TP0598; Hypothetical protein; identified by Glimmer; putative.
   
 0.954
TP_0262
Catabolite gene activator (crp); Similar to GB:J01598 SP:P03020 PID:145594 PID:606291 GB:U00096 percent identity: 29.19; identified by sequence similarity; putative.
 
 
0.939
TP_0263
Conserved hypothetical protein; Similar to GB:AE000783 percent identity: 24.22; identified by sequence similarity; putative.
 
     0.933
Your Current Organism:
Treponema pallidum
NCBI taxonomy Id: 243276
Other names: T. pallidum subsp. pallidum str. Nichols, Treponema pallidum Nichols, Treponema pallidum subsp. pallidum str. Nichols
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